Category Archives: Serotonin Effects
Where can I buy serotonin tablets?
Anyone searching for serotonin tablets will find them in any number of supermarkets, usually somewhere between the pixie dust and Honest John’s cure-all elixir. And if you’re still not convinced about the lack of benefits of serotonin tablets you may be interested in one of my many proven snake oil potions.
The simple explanation why serotonin tablets are as rare as an Obama loving Fox News presenter is that they simply do not work. Although, admittedly, a medication’s inability to do the job does not always prevent Big Pharma from trying to peddle it.
All this does not mean that serotonin boosting medication does not exist. Serotonin reuptake inhibitors are one of the most wisely prescribed medications in the developed world. While there are also two serotonin supplements that could also have the desired effect of serotonin pills.
Believe it or not, our brain is rather selective in which chemicals it allows to enter. Although Red Sox supporters do provide good reason to dispute this. Chemicals pass from our blood, into our brain, through an array of channels. Each of the channels is shaped in a particular way so as only to allow access to certain shaped molecules. A number of tiny electrical charges also add to the conundrum. Such a blockade is commonly termed the blood brain barrier. For whatever reason, we don’t have any channels that allow serotonin access to our brain, although in the case of Fox News viewers, that would be like trying to squeeze a basketball into an egg cup.
What Would Serotonin tablets Do?
While it is assumed that anyone in search of the “Holy Grail’ that is serotonin tablets, is doing so to relieve depression, let’s just remind ourselves of what would happen if we really could get hold of the happy hormone in its purest form. First of all, as serotonin effects explains, serotonin does more than make a visit from the mother-in-law palatable.
For one, it’s going to have you rushing to the toilet and having to decide through which end you are going to extract the contents of your gut. Secondly, by causing your blood vessels to constrict, any serotonin that escapes the gut is going to put your heart into overdrive.
Put bluntly; serotonin may well be the bringer of happiness, and it is truly a remarkable compound, however; too much in the wrong place is going to have you begging for mercy from every god that never walked. If you really want to increase you serotonin via medication, the nearest you’re going to get to serotonin tablets you may need to look at how to increase your serotonin.
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Anyone wanting to know about serotonin will obviously want to know about the most lethal of its effects.Before moving on to serotonin syndrome symptoms, let’s just answer the question what is serotonin syndrome? To put it bluntly serotonin syndrome is the effects of too much serotonin in our body as a whole, and not just our brain.
You may think that for what is nothing more than an overdose of serotonin, the term ‘syndrome” is a more than little mystifying. However there is more to it. While the result maybe too much serotonin, the actual serotonin overdose is usually of an accident of nature.
High serotonin levels are the cause of serotonin syndrome, but a simple overdose of serotonin supplements is rarely, if ever, the cause. The main causes of serotonin syndrome are medications prescribed for depression, and recreational drugs. The third being interactions between different prescribed drugs taken at the same time.
One of the most common drugs used to treat depression is selective serotonin reuptake inhibitors (SSRIs). While this on its own can create increased levels of serotonin, the biggest danger lies in mixing them with other medication. Obviously any other form of antidepressant is going to increase the effects. However, there are more routes to serotonin syndrome.
Taking an SSRI, usually to treat depression, alongside migraine medication such as triptans may trigger an adverse reaction. Likewise, recreation drugs, such as LSD the Fox News presenters’ favorite, or amphetamine and ecstasy are the more obvious ones. While just to show that natural does not al\ways mean safe, St John’s wort is a natural SSRI and should not be taken with prescribed variations.
What are the serotonin syndrome symptoms?
Serotonin syndrome symptoms can begin to appear within a few minutes to a few hours. Plasma serotonin is known to have an effect on blood vessels and so will cause variations in blood pressure. Where the digestive system is concerned; the symptoms of serotonin syndrome are; vomiting, diarrhea and nausea. Increases to body temperature and sweating, a higher heartbeat and also lack of coordination are also common serotonin symptoms.
Other serotonin syndrome symptoms, also common to other neurotransmitter fluctuations are hallucinations and restlessness.
How to treat serotonin syndrome
Serotonin syndrome requires urgent medical treatment. The most obvious first step is cessation of medication. This is then taken a step further with medication to block serotonin production. Fluids such as electrolytes will be given intravenously. Muscle relaxants then complete the standard treatment which hopefully will rapidly reduce the serotonin syndrome symptoms.
The only apparent serotonin withdrawal arises out of withdrawal from SSRIs. Such symptoms are discussed in serotonin reuptake inhibitors.
Read more about serotonin syndrome symptoms
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At a very basic level, serotonin and sleep do not make the best of bed fellows. Serotonin is more associated with alertness and mood. Any increase in serotonin is liable to promote wakefulness. This explains why sleeping when hungry is difficult. Hunger causes our liver to release its store of amino acids to be used as energy. This ultimately increases the supply of tryptophan, the precursor of serotonin.
Of the many functions of serotonin we shouldn’t be surprised to discover there is a link between sleep and serotonin. However; the relationship is not all one way. While serotonin does affect sleep, at least indirectly, sleep also influence the effectiveness of serotonin.
Serotonin and sleep; the melatonin effect upon sleep
In this process serotonin, a neurotransmitter is converted to melatonin, a hormone. For those of us who have better things to do than remember what they are. Neurotransmitters carry signals over the junctions of neurons. We could say they bridge the gap between neurons and allow signals to travel around our brain. Hormones also carry messages, but this time they carry messages in our blood and brain fluids. Essentially this process is another demonstration of waste not want not. Something that nature has developed into a fine art.
Another major difference is that neurotransmitters are made by cells. Hormones on the other hand are made by the glands and organs of the endocrine system. While there is undoubtedly a link between serotonin and sleep, it is usually melatonin that is referred to as the sleep hormone. The two chemicals are very similar in everything apart from their action.
During the night, or more precisely in the absence of blue light, serotonin is converted to melatonin. This production peaks around 3 – 4 am and is one of the features of our circadian rhythm. The mechanisms through which many of our processes are regulated according to the time of day. The organ responsible for this function that connects serotonin and sleep is the pineal gland.
The reverse serotonin sleep effect
The next connection between serotonin and sleep is in the opposite direction. Here it is sleep; or rather lack of sleep that influences serotonin’s effectiveness. To carry out its duty, serotonin, after being released, must attach itself to a receptor site. Unfortunately, such receptor sites can be a little temperamental. They become insensitive to serotonin and prevent it from attaching. Essentially the serotonin receptor sites become desensitized and reduce serotonin’s capacity to transmit signals.
The danger lies in the creation of a vicious circle. Anything that interrupts the serotonin and sleep pattern can then lead to reduced effectiveness of serotonin throughout the day. Serotonin imbalances and its links with depression have been known for years. However, the actual mechanisms are now being disputed. Additionally, as serotonin syndrome shows, the effects of trying to re balance any serotonin deficit can have serious repercussions.
The old school thought that it was serotonin’s effect on our brains signaling capacity that influenced depression.. However, now it is being argued that it is serotonin’s contribution to making of new brain cells(neurogenics) that influences depression. Regardless of which is correct, no one can argue that where serotonin and sleep are concerned; serotonin effects sleep effects serotonin.
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Occasionally feeling a little down the dumps cannot, by any stretch of the imagination, be regarded as clinical depression. What is also now being disputed are the actual mechanisms of serotonin depression. While no one disputes the claim that increasing the amount of serotonin in our brain, focus is now shifting towards where in the brain it actually impacts.
Does Serotonin depression exist?
There are well recognized links between depression serotonin and sleep. However the current hypothesis that increasing the level of serotonin enables better coordination between cells is not standing up to scrutiny. Rather alarmingly it is being suggestion that the reason we are told that the “Prozac” style of medication is so effective, is because it redresses our serotonin imbalance.
It is now being argued that serotonin depression due to a serotonin imbalance is myth, perpetuated by manufacturers and the medical profession, albeit for different reasons. Firstly the medical profession say that we are more likely accept the diagnosis of serotonin imbalance, and subsequent treatment of, than other less flattering conclusions.
The second reason is to the benefit of the SSRI manufacturers. It is generally accepted that a very efficient treatment, with very relatively few side effects, already exists. Therefore no alternative will be sought.
In all honesty the traditional serotonin depression link; or at least the SSRI depression link has little supporting evidence other that the end result. This is all that we can be sure of. In essence we are fed this bullshit because it is easier for us to understand, regardless of the risk of serotonin syndrome, or any other serotonin side effects.
The crux of the argument is that selective serotonin reuptake inhibitors, 5-HTP and tryptophan supplements, treat the symptom and not the cause of depression. The serotonin depression connection still exists, but not in the place we have been lead to believe.
Serotonin and Neurogenesis, the real cause of depression?
Serotonin also plays a role in neurogenesis, the birth of new neurons. While the rate of neurogenesis does slow with age, people diagnosed with depression have an abnormally lower rate of neurogenesis. Increasing this growth rate has proven to relieve depression.
The way that stress is thought to cause depression provides further evidence to support this hypothesis. Exposure to stressful situations increases the release of cortisol. Cortisol is thought to cause damage to neurons. This then creates a demand for more new neurons that in turn increases the demand for serotonin. Ultimately bring us back to the serotonin depression scenario.
Ultimately, with the behavior of both the medical profession and big pharma, that plant and wasp stings not the only third party serotonin effects. If you would like to read more about serotonin depression you may like to read this
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